The Saints overturned a deficit to claim their 17th consecutive unbeaten match, with second-half goals from Leo Scienza and Taylor Harwood-Bellis securing the three points. Despite a strong start from the hosts, Derby took the lead through Carlton Morris, but Southampton's persistence eventually paid off. The visitors were forced into an early change when Bobby Clark was replaced by Oscar Fraulo, and although they showed intent, the Saints' superior possession and chances ultimately told. Scienza's curling finish and Harwood-Bellis's headed goal from a Ryan Manning free-kick sealed the win, leaving Derby to rue their missed opportunities and a rare test for Daniel Peretz in the Saints' goal.
The result keeps Southampton in the hunt for a playoff spot, while Derby's defeat leaves them three points adrift of their opponents.